Cytochrome c is a vital protein found in the mitochondria of cells, playing a crucial role in energy production and the regulation of apoptosis, or programmed cell death. This protein is involved ...

In multicellular organisms, the total number of cells is a balance between the cell-generating effects of mitosis and cell death that is induced through apoptosis. A disruption of this delicate ...

The oxidative stress activates Nrf2/Keap1. MEQ upregulated Bax/Bcl-2 ratio, disrupted mitochondrial permeability transition pores, and subsequently, caused cytochrome c release and a cascade ...

Bcl’s act by inhibiting release of cytochrome C from mitochondria in the cytoplasm, cytoplasmic cytochrome C leads to apoptosis via a caspases cascade. Apaf1 inhibition + Hsp70. Hsp90/Hsp70 complex ...

When Seamus J. Martin, professor of medical genetics at the Smurfit Institute, Trinity College in Dublin, Ireland, and colleagues began their work, they knew of an apoptosis pathway involving ...

This was associated with translocation of cytochrome-c from the mitochondria to the cytosol, resulting in activation of the caspase cascade via caspase-9. Key executioner enzymes were caspases-3 and ...

Anxiety-like Behavior,Bax Protein,Brain-derived Neurotrophic Factor,Cytochrome C,Effects In Mice,Elevated Plus Maze,Elevated Plus Maze Test,Epilepsy In Mice,Hematoxylin And Eosin,Hippocampal ...

ClC-3 deficiency promoted DSS-induced apoptosis of intestinal epithelial cells through the mitochondria pathway. ClC-3 interacts with voltage-dependent anion channel 1, a key player in regulation of ...