Gap junctions are specialized structures that ... Studies have shown that Cx43 hemichannels contribute to astrocyte-mediated neurotoxicity in ALS, and the knockout of Cx43 in astrocytes can ...

astrocyte-to-astrocyte transmission through gap junctions, as well as paracrine release of ATP, might modulate synaptic biology. Nicholas Maragakis is an assistant professor of neurology at the ...