在骨髓中,myHSCs和淋巴系造血干细胞(lyHSCs)的数量对比进一步显示了Sema4A缺失对髓系细胞的过度偏向(g、h)。特别是髓系前体细胞(MyPro)和红系前体细胞(CFU-E)的数量变化,也支持了Sema4A缺失与髓系扩展的关系。
Comparison of the LSC expression data to that of normal hematopoietic stem cells (HSC) revealed that 34% of the modulated genes are shared by both LSC and HSC, supporting the suggestion that the ...
A study finds that shared care between HCT specialists and local oncologists improves early quality of life without ...
This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...
To see whether beta-blockers affect human hematopoietic cell transplants, Dr. Morrison collaborated with Stephen Chung, M.D., Assistant Professor of Internal Medicine in CRI and member of the ...
Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a ...
The combination of treosulfan and fludarabine as a preparative regimen for allogeneic hematopoietic stem cell transplantation ...
The FDA has approved GRAFAPEX™ and fludarabine as a preparative regimen in acute myeloid leukemia or myelodysplastic syndrome ...
(IN BRIEF) AstraZeneca’s Calquence (acalabrutinib) has been approved by the U.S. FDA for the first-line treatment of adult patients with previously untreated mantle cell lymphoma (MCL) who are ...