在骨髓中，myHSCs和淋巴系造血干细胞（lyHSCs）的数量对比进一步显示了Sema4A缺失对髓系细胞的过度偏向（g、h）。特别是髓系前体细胞（MyPro）和红系前体细胞（CFU-E）的数量变化，也支持了Sema4A缺失与髓系扩展的关系。

Comparison of the LSC expression data to that of normal hematopoietic stem cells (HSC) revealed that 34% of the modulated genes are shared by both LSC and HSC, supporting the suggestion that the ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

A study finds that shared care between HCT specialists and local oncologists improves early quality of life without ...

Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a ...

First, the major dose-limiting toxicity for many chemotherapeutic agents is hematopoietic. In HSCT, this becomes a moot point, as new HSCs will be reinfused, thus allowing a dose escalation of the ...

Hematopoietic stem cell transplantation (HSCT) plays a significant therapeutic role in treating these patients. Theodore B. Moore, MD, Director, UCLA Pediatric Bone Marrow Transplant Program ...

The FDA has approved GRAFAPEX™ and fludarabine as a preparative regimen in acute myeloid leukemia or myelodysplastic syndrome ...

The combination of treosulfan and fludarabine as a preparative regimen for allogeneic hematopoietic stem cell transplantation ...