Genetic polymorphisms have been described in the case of several CYP isoenzymes ... mediated interactions Ticlopidine ↑ PPI effect Inhibition of omeprazole 5'-hydroxylation, decreased ...

Xia Wen In vitro approaches in evaluation and prediction of drug-drug interactions involving the inhibition of cytochrome P450 enzymes. Teemu Kantola, Effects of itraconazole and some other CYP3A4 ...

Omeprazole is metabolized directly in part by CYP3A4 to omeprazole sulfone ... CYP2C19-mediated interactions Ticlopidine ↑ PPI effect Inhibition of omeprazole 5'-hydroxylation, decreased ...

For example, Ubrelvy can interact with certain drugs called strong CYP3A4 inhibitors, such as clarithromycin. Ubrelvy is taken by adults to treat certain kinds of migraine episodes. An interaction ...

Renal or hepatic impairment: initiate at lower doses; monitor. Concomitant use or discontinuation of CYP3A4 inhibitors or inducers: monitor closely and consider dose adjustments (see full labeling).

May be potentiated by systemic CYP3A4 inhibitors, dual CYP3A4/CYP1A2 inhibitors (eg, erythromycin, ketoconazole, fluvoxamine, enoxacin, cimetidine); consider risks vs benefits prior to concomitant ...