Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts.

Platelets originate from megakaryocytes, which are precursor cells in the bone marrow that develop from pluripotent stem cells by a multistep process. [4–7] ...

A new UCSF study shows that the human lungs have just as many blood-producing stem cells as bone marrow. These stem cells are ...

GPIIb/IIIa and other platelet-related antigens. In addition to direct pathogenic effects of antibodies on megakaryocytes, there is evidence that cell-mediated cytotoxicity, complement activation ...

Platelets are derived from megakaryocytes, cells found in the bone marrow. The team explained that platelets, when they break off megakaryocytes and enter the bloodstream, often take small pieces ...

The platelets numbered 59,000 per cu. mm., and megakaryocytes without platelet formation were present in the bone-marrow aspirate in normal numbers. On June 9, the platelets again numbered 60,000 ...

Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion ...

In a groundbreaking discovery, researchers at UCSF have found that the lungs, not just the bone marrow, play a crucial role ...

No megakaryocytes were seen. Androgen and steroid therapy was discontinued, and treatment with intermittent platelet and blood transfusions was begun. Response to transfusion of fresh platelet ...

They found hematopoietic stem cells (HSCs) in human lung tissue that make red blood cells, as well as megakaryocytes, which produce the platelets that form blood clots. The findings appear Feb. 27 ...