Each of these synapses consists of a single postsynaptic density containing numerous glutamate receptors apposed to a presynaptic ribbon-type active zone of neurotransmitter (glutamate)-filled ...
With advancing age, the prevalence of vestibular deficits increases; yet, the underlying mechanisms are not well understood and the possible accompanying morphological changes in the VHC synapses have ...
Based on these findings they are currently investigating the essential functions some of these adhesion links ensure in the photoreceptor cells. They have shown that the hair cell ribbon synapse is ...
Additionally, the SNARE protein SNAP-25 has been identified as crucial for normal exocytosis at auditory hair cell ribbon synapses. Studies involving conditional knockout mice demonstrated that ...