Although the mTOR pathway has been characterized in T cells, it has not been well described in other immune cells. In this study, Weichhart et al. investigated how mTOR activity in phagocytes ...

相关研究结果于2025年1月1日在线发表在Nature期刊上，论文标题为“Dysregulation of mTOR signalling is a converging mechanism in lissencephaly”。 论文共同通讯作者 ...

A study led by Dr. Peter Canoll's lab, in collaboration with researchers at Columbia University Irving Medical Center, ...

A Columbia-led study uncovers how gliomas cause seizures and cognitive impairments by disrupting brain activity. Using ...

In a nutshell A common desert plant called Artemisia herba-alba contains compounds that can effectively kill colorectal ...

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

Their findings pointed to dysregulation in the mTOR (mammalian target of rapamycin) pathway in both types of lissencephaly organoids they were studying. "This is a fundamental pathway that governs ...

Seventeen tumor samples from 14 patients with SDH-deficient GIST underwent NGS. Mutational load was low, although three patients (21%) displayed molecular events in relapse samples leading to ...