The recommended Phase II dose of abiraterone acetate is 1000 mg orally daily in combination with prednisone 5 mg twice daily. Side effects are minimal and mostly associated with secondary ...
The treatments, after informed consent signature, were administered at standard doses: AA 1000 mg once a day in combination with prednisone (5 mg twice daily) and ENZ 160 mg once a day.
In a phase III, double-blind, randomized setting, LATITUDE tested androgen deprivation therapy (ADT) with abiraterone acetate (AA ... and then randomized 1:1 to either ADT + AA (1000 mg daily) + ...
All eligible patients received salvage radiotherapy plus 6 months of a GnRH agonist and randomization was to concurrent bicalutamide 50 mg or abiraterone acetate/prednisone 1000 mg/5 mg +apalutamide ...