Notch1 deficiency impairs the transcription of genes involved in mitochondrial fusion and biogenesis, thereby triggering aortic pathology. Early intervention to enhance these mitochondrial ...

The coexistence of transthyretin cardiac amyloidosis (ATTR‐CA) and aortic stenosis (AS) is increasingly recognized, but the clinical consequences are unclear. We aimed to characterize clinical ...

There was free aortic regurgitation because of dilatation ... From the departments of Surgery and Pathology, Harvard Medical School, and the General Surgical Services and the James Homer Wright ...

Boy Abunda reported the cause of death on Tuesday's episode of "Fast Talk with Boy Abunda," saying he got on a call with Savellano's wife, Dina Bonnevie. An abdominal aortic aneurysm occurs when there ...

The most commonly used classifications are based on the affected anatomical portion. The Stanford group considers: type A (dissection involving ascending aorta) and type B (descending aorta only). 7 ...

This time, doctors performed thorough scans, and transferred her to the National Heart Centre Singapore (NHCS). She was diagnosed with severe aortic stenosis. This is a degenerative heart condition in ...

Atherosclerotic plaques are a feature of abdominal aortic aneurysms (AAAs). Atherosclerosis and AAA appear to share similar risk factors. These observations have led to the conclusion that AAAs ...

Figure 1. The natural history of aortic stenosis, emphasizing a long presymptomatic period and the dismal outcome once symptoms begin. AV indicates average. Adapted from Ross and Braunwald. 11 In the ...

Of 49 patients who underwent repair of their thoracic aorta, pathology was available for 25, of whom 52% had evidence of cystic medial degeneration. Mortality rates did not deviate from those of ...