Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components of the internal immune cells, which profoundly affects the internal ...

What is the immune system? The immune system works to keep germs and other foreign substances out of the body and destroy any that get in. It's made up of a complicated network of cells and organs. It ...

To measure CCL2 in highly enriched neuronal culture supernatants, ELISA plates (96-well) were coated with corresponding mouse anti-human antibodies (1–2 μg/ml) overnight at 4°C. The plates ...

Patricia F. Lalor, Ph.D.; 1 Jeff Faint, Ph.D.; 1 York Aarbodem, M.Sc.; 1 Stefan G. Hubscher, F.R.C.Path.; 1 David H. Adams, M.D., F.Med.Sci.1 1 Liver Research Group ...

Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and ...

It feels like the Splinter Cell remake has been on its way for a while now, which isn't helped by the fact it's been over three years since we heard anything official about the game. From what we ...

IL-6 and CCL2 mRNA levels were observed to significantly ... neuronal subtypes, microglia, and endothelial cells organized in a 3D manner. This approach enables a more accurate representation ...

The majority of the 27 immunological markers measured were elevated in deceased patients compared to those who survived. Increased levels of IFNγ, CCL2, and CCL3 were particularly associated with ...

Endothelial cells are, by number, one of the most abundant cell types in the heart and active players in cardiac physiology and pathology. Coronary angiogenesis plays a vital role in maintaining ...

Angiopep-2 (Ang2) is an oligopeptide that can target the blood–brain barrier. Through single-cell sequencing and immunofluorescence experiments, we confirmed that the expression of LRP-1, the targeted ...

Here we focus on findings in the CCL2-CCR2 and CCL3-CCR5 ligand-receptor systems. The roles of these molecules in regulating T cell fate include possible indirect effects on antigen-presenting ...

The latter involves several complex mechanisms like endothelial cushion formation and smooth muscle cell migration resulting in fibrosis and sealing of the vessel. These complex steps indicate ...