Here we focus on findings in the CCL2-CCR2 and CCL3-CCR5 ligand-receptor systems. The roles of these molecules in regulating T cell fate include possible indirect effects on antigen-presenting ...
Patricia F. Lalor, Ph.D.; 1 Jeff Faint, Ph.D.; 1 York Aarbodem, M.Sc.; 1 Stefan G. Hubscher, F.R.C.Path.; 1 David H. Adams, M.D., F.Med.Sci.1 1 Liver Research Group ...
Researchers reveal that the loss of mucin-type O-glycosylation in the brain endothelial glycocalyx weakens the blood-brain ...
A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce ...
and largely shuts down these cells' interactions with surrounding marrow cells, in particular the specialized endothelial cells that compose the blood vessels. FLI-1's activity, in contrast, restores ...