While manganese is an essential mineral involved in many bodily functions, both deficiency and excessive exposure can cause ...
Its pathological hallmark is the abnormal aggregation of α-synuclein (α-syn) into insoluble fibrils and Lewy bodies, leading to the degeneration and death of dopaminergic neurons in the ...
A novel wireless photothermal DBS nanosystem uses nanoparticles to target and restore damaged neurons in Parkinson’s disease, ...
In the BlueRock trial, an unnamed patient has now been administered the first dose of pluripotent stem cell-derived dopaminergic neurons – MSK-DA01 – via a surgical transplant procedure into ...
These preferences are mediated by different neuronal circuitry in male and female mice related to dopaminergic neurons in the brain’s ventral tegmental area, the researchers found. The findings ...
Manganese exposure raises the risk of Parkinson's disease, but biotin might be the key to preventing manganese-induced brain ...
Utilizing dual-color fiber photometry calcium recordings alongside projection-specific chemogenetic and optogenetic manipulations of dopaminergic neurons in the ventral tegmental area (VTA), the ...