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Maintaining treatment with CDK4/6 inhibitors significantly suppresses the growth of breast cancer cells, even after drug resistance has developed, according to new research.
Targeting the HSF1 pathway with the inhibitor NXP800 decreases HSP72 expression, activates the unfolded protein response, and inhibits AR- and E2F-mediated activity, inhibiting the growth of treatment ...
"This work is an effort to understand how the activity of E2F is coordinated with the cell cycle. We show that regulation of E2F involves an interaction with Rb in G1, whereas in S phase, E2F forms a ...
People with diabetes should eat as much protein as people who don't have diabetes. In a healthy diet, roughly 10% to 35% of your daily calories should come from protein. Protein itself does not have ...
Scroll through TikTok or Instagram and you’ll be inundated with protein-centric recipes. Maximizing protein is a huge trend right now on social media—and not just in the usual suspects ...
I'm a Fitness & Nutrition writer for CNET who enjoys reviewing the latest fitness gadgets, testing out activewear and sneakers, as well as debunking wellness myths. On my spare time I enjoy ...
Best whey-protein powders Best collagen-protein powder Best plant-based protein powders All the other protein powders I’ve tried Protein powders can be found in thousands of formulations on tens ...
The best protein shakers are a must-buy, so we've tried and tested the best on the market to help you decide what to carry before, during and after your workouts. And we've done that much testing ...
Featured pricing is subject to change. We know the feeling — the feeling of waltzing down a supermarket aisle to find the best protein bars, but getting too overwhelmed that we just put our ...
This study presents fundamental insights into overcoming resistance in hormone receptor-positive breast cancer by demonstrating that sustained CDK4/6 inhibitor treatment, either alone or in ...