Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China Key ...

G protein-coupled receptors (GPCRs) remain a focal point of research due to their critical roles in cell signaling and their prominence as drug targets. However, directly linking drug efficacy to the ...

After hours: March 10 at 7:29:36 PM EDT Loading Chart for GPCR ...

Regulation of GPCR signaling by RGS12. The Gβγ heterodimer serves to couple Gα to the receptor and to inhibit its spontaneous release of GDP. Genes & Diseases publishes rigorously peer-reviewed ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these ...

This study makes the fundamental discovery of the first natural animal rhodopsin that uses a chloride ion instead of an amino acid side chain as a counterion. Using a combination of biochemical and ...

In NAc astrocytes, D1R-mediated signaling is complex ... These findings about astrocytic GPCRs in drug addiction are significant. They not only enhance our understanding of the cellular mechanisms ...