Future Oncol. 2010;6(5):665-679. Three Phase I studies by O'Donnell and colleagues have reported the pharmacodynamic activity of abiraterone acetate, which was originally developed as an oral ...

Abiraterone acetate (CB7630), a pregnenolone analog, is an orally administered small molecule that irreversibly inhibits a rate-limiting enzyme in androgen biosysnthesis, CYP17, and blocks the ...

the prostate cancer drug abiraterone, and the HIV medicine lamivudine. The latter was marked up to quadruple of what the so-called "Big 3 PBMs" paid for it, the FTC found. Overall, the "Big 3 PBMs ...

The FTC report found that from 2017 to 2022, three PBMs—UnitedHealth Group's Optum, CVS Health's CVS Caremark and Cigna's ...

In Apotex Inc. v. Janssen Inc., 2022 FC 1473, Janssen markets prostate cancer drug abiraterone acetate in Canada as ZYTIGA, which is listed in the patent register as the 422 Patent. Apotex, Dr.

In 2012, Alfred was diagnosed with advanced prostate cancer which had already spread to his bones. As surgery wouldn’t have been effective, Alfred enrolled in the Cancer Research UK-funded STAMPEDE ...