Meibomian glands are critical to the ocular health in that they secrete lipid-rich meibum, which protects the ocular surface ...

Janus kinase/signal transduction and transcription activation (JAK/STAT ... QB and JZ completed the literature collection. JM, QH, LW, HH, and PW revised the manuscript. All authors approved the final ...

pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems and play a role in BCC. The requirement ...

The researchers identified markers for stem cell populations that maintain distinct regions of the meibomian glands, and uncovered the hedgehog (Hh) cell-cell signaling pathway, which is broadly ...

In cancer cells, abnormal activation of signaling pathways can widely affect cell activity from growth and proliferation to apoptosis, invasion and metastasis. Wnt/β-catenin is a complex and unique ...

The researchers identified markers for stem cell populations that maintain distinct regions of the meibomian glands, and uncovered the hedgehog (Hh) cell-cell signaling pathway, which is broadly ...

Research reveals howneurogenic connection can directly trigger inflammatory processes, creating pain patterns that challenge ...