The SAMP mice, including SAMP8, have been widely used in aging research to study phenotypes such as immune dysfunction, osteoporosis, and brain atrophy. The mice have apparently normal early ...
“I can start mapping those to different compounds and just start adding those compounds in my cultures in the accelerated aging machine and see which ones work to reverse aging pathways in the immune ...
Accelerated brain aging is a risk factor for dementia ... progeny—neutrophils—and acting via a negative feedback loop. Immune dysfunction increases with age owing to cellular senescence ...
Female mammals typically carry two X chromosomes — one from each parent — and a new study suggests that the maternal X is linked to faster brain aging.