Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on their surfaces. This protein, called the ...

The primary aim is to connect fundamental research with clinical application to optimize the efficacy of γδ T cell therapy for cancer. Figure 1. Major receptor-ligand recognition between Vδ2/Vδ1 T ...

Delhi, Jan. 29, 2025 (GLOBE NEWSWIRE) -- Global Gamma Delta T Cell Cancer Therapy Market Opportunity and Clinical Trials Insight 2030 Report Conclusions: Global Gamma Delta T Cell Therapy Clinical ...

The three-signal paradigm tries to capture how the innate immune system instructs adaptive immune responses in three well-defined actions: (1) presentation of antigenic peptides in the context of MHC ...

Intratumoral T cell activation by MATE-expressing oncolytic viruses sensitizes tumors to PD-1 checkpoint inhibitor therapy. We have generated membrane-associated T-cell engager molecules (MATEs) ...

Supervised Exercise for Patients With Metastatic Breast Cancer: A Cost-Utility Analysis Alongside the PREFERABLE-EFFECT Randomized Controlled Trial Colorectal cancer (CRC) remains a major global ...

We recapitulate these values in Table. 1. However, human data show a great diversity depending on many factors such as tumor edge, patient age, non-cancer health status, as well as method of analysis.