Existing research indicates that exosomal long non-coding RNAs (lncRNAs) play a crucial regulatory role in the initiation and progression of tumors, involving various interactions such as lncRNA-miRNA ...
近日,中国科学院上海有机化学研究所生物与化学交叉研究中心胡姣姣博士及刘聪研究员受邀在 Molecular Cell 杂志发表题为 “LncRNAs chaperoning dynamic protein condensates in cancer cells” 的文章,对同期同刊发表的关于 lncRNA 调控蛋白相分离的相关研究进行了深度解读与 ...
该研究首次发现,肠道微生物群通过抑制长链非编码RNA(lncRNA)Snhg9,发挥限制结直肠肿瘤发生发展的作用。 肠道微生物群是结直肠癌(CRC ...
该研究首次发现,肠道微生物群通过抑制长链非编码RNA(lncRNA)Snhg9,发挥限制结直肠肿瘤发生发展的作用。 肠道微生物群是结直肠癌(CRC)发生发展的关键环境因素。该研究发现,在结肠轻度炎症的情况下,肠道微生物群对小鼠结直肠肿瘤的发生具有保护作用。
The prehybridized slides were then incubated with lncRNA-probe in hybridization solution at 37°C for 16 h. After hybridization, the slides were washed six times with prewarmed wash buffer and PBS ...
HOXA10 antisense RNA (HOXA10-AS, also known as HOXA-AS4) is a novel lncRNA that was identified to be dysregulated in some prevalent malignancies. In this review, the clinical significance of HOXA10-AS ...
We identified a total of 153 m6A-related lncRNAs in pRCC datasets, of which six were selected for constructing a m6A-related lncRNA pRCC prognostic model. Mutations in the SETD2 gene correlated with ...