The crystal structure of the hemagglutinin of both the viruses is similar, especially within the Sa antigenic site. Compared with seasonal influenza outbreaks, the overall impact of the 2009 H1N1 ...

If this occurs, H5N1 could potentially start spreading from human to human. Influenza viruses are covered with two lollipop-shaped proteins called hemagglutinin and neuraminidase, for which the ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

Their immunogen composition is revised biannually to optimally match the antigenic drift of the hemagglutinin of circulating influenza virus strains ... The NA catalytic pocket is indicated on one of ...