FDA approval of PATHWAY HER2 (4B5) test expands diagnostic capabilities for HER2-ultralow metastatic breast cancer, enabling targeted treatment with trastuzumab deruxtecan. HER2-ultralow ...

The EMA has started a review of AstraZeneca and Daiichi Sankyo's antibody-drug conjugate (ADC) that could see the drug being used in advanced breast cancer with even lower levels of the HER2 ...

Breast cancer classed as HER2-positive – defined as an immunohistochemical (IHC) score of three or more – accounts for somewhere between 20% to 25% of all patients with the disease.

Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...

On January 27, the Food and Drug Administration (FDA) expanded the approval of Enhertu (fam-trastuzumab deruxtecan) to cover people with hormone-positive, HER2-ultralow advanced breast cancer ...

An irate New Jersey man viciously murdered a family in a stabbing rampage that targeted his ex-girlfriend and her two young children, with the accused then attempting to turn the knife on himself ...

Some eight years since the Nintendo Switch was released, we have finally got an official look at the Nintendo Switch 2. In a rather brief trailer, Nintendo showed off its next-generation gaming ...

But she’s since shared a lengthy video on TikTok with her 2.5 million followers in which she named Paul as the influencer, claiming the stunt was purely to “lure new customers over” to the X ...

We then summarize several current routes to identify new drugs such as cationic antimicrobial peptides, novel acyldepsipeptides, RNA aptamers and lipopeptides. New drug strategies to treat ...

Marion County Jail An Indiana mom is accused of neglecting her children for long periods of time in her home, culminating when she allegedly found her 2-year-old daughter dead under a dresser.

DeAndre Booker has been charged with premeditated murder and tampering with evidence Samira Asma-Sadeque is a legal reporter at PEOPLE's crime desk. Her work includes writing about crime ...

Nintendo Switch 2 is finally confirmed. After literal years of unverified rumors, dubious leaks and copious amounts of online speculation, Nintendo has lifted the lid on its next-generation ...