Research spanning more than 20 years has led the UPV/EHU's Neurochemistry and Neurodegeneration group under Dr. Rafael Rodríguez-Puertas to discover a promising avenue for the development of new ...

The studies suggest that mutant KRAS signals predominantly through the rapidly accelerating fibrosarcoma (RAF) effector pathway ... MEK mitogen-activated protein kinase kinase, MT mutant, Pi ...

Introduction: Bryostatin-1, a potent agonist of the protein kinase C, has been studied for HIV and cancer therapies ... These changes were confirmed through RNA-seq analysis. RNA-seq revealed that ...

"Rasopathies are a group of rare genetic disorders that are caused by mutations in genes that regulate the Ras/mitogen-activated protein kinase (MAPK) signaling pathway." "Given the rarity of this ...

The pig cardiomyocyte cells also showed upregulation of three signaling pathways — the Mitogen-Activated Protein Kinase pathway, the HIPPO/YAP pathway and the Transforming Growth Factor Β pathway.

The pig cardiomyocyte cells also showed upregulation of three signaling pathways -- the Mitogen-Activated Protein Kinase pathway, the HIPPO/YAP pathway and the Transforming Growth Factor Β pathway.

Kinases have a pivotal role in phosphorylation and kinase dysregulation has been implicated in the occurrence and progression of various diseases. By mid-2024 the Food and Drug Administration had ...

New research reveals groundwater pathways across continent. ScienceDaily . Retrieved February 1, 2025 from www.sciencedaily.com / releases / 2025 / 01 / 250107161842.htm ...

Figure 5: Cell-survival pathways downstream of activated erbB receptor tyrosine kinases. The Ras–MAPK (mitogen-activated protein kinase) pathway is another important cell-proliferation pathway ...

B-cell receptor-activation pathways following antigenic stimulation. BCR: B-cell receptor; BLNK: B-cell linker protein; BTK: Bruton's tyrosine kinase; DAG: Diacylglycerol; GSK: Glycogen synthase ...