Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...

Mitoribosomes are present in the mitochondria of all eukaryotic cells. Their function is to allow the translation of mitochondrial mRNA that exclusively encodes components of the oxidative ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

1. 澳大利亚纽卡斯尔大学的研究发现，抑制线粒体氧化磷酸化(oxphos)能抑制糖酵解功能健全的结直肠癌(crc)细胞的增殖和致瘤性。 2. 研究结果显示 ...

The first human trial of insulin-producing cells that have been gene-edited to evade immune attack is a success so far. The cells have survived and produced insulin for a month after being ...

This complex process, known as gene expression, determines which proteins we make and whether we make them in the correct amounts, crucial work given that proteins play a role in virtually every a ...

A ba­by boy born with a de­bil­i­tat­ing ge­net­ic dis­ease will like­ly no longer re­quire a liv­er trans­plant to sta­bi­lize his con­di­tion, thanks to a first … ...

Summary: Researchers have developed an AI model that accurately predicts gene activity in any human cell, providing insights into cellular functions and disease mechanisms. Trained on data from over 1 ...

The same is now possible in gene editing. Rather than employ separate tools for editing genes and regulating their expression, these distinct goals can now be combined into a single tool that can ...

Some genes are beneficial and enhance longevity. For example, the gene that helps a person metabolize cholesterol would reduce a person's risk of heart disease. Some gene mutations are inherited.

In this report, the authors made use of a murine cell life derived from a MYC-driven liver cancer to investigate the gene expression changes that accompany the switch from normoxic to hypoxia ...