RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns ...

在前列腺癌的研究领域，美国杜克大学医学院杜克癌症研究所前列腺与泌尿系统癌症中心的 Muthana Al Abo 等研究人员取得了一项重要进展。他们的研究成果《Genetic ancestry concordant RNA splicing in prostate cancer involves oncogenic genes and associates with recurrence》发表于 ...

SEED Therapeutics Inc. has announced that its molecular glue therapy, ST-01156, has been granted Rare Pediatric Disease and ...

SEED Therapeutics announced that the U.S. Food and Drug Administration has granted Rare Pediatric Disease and Orphan Drug designations to ...

Rising demand for precision medicine & groundbreaking innovations in RNA sequencing drive growth in oncology, drug discovery, & personalized therapies. Akash Anand SNS Insider Pvt. Ltd 415-230-0044 ...

The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

A new study from the Kowalinski group at EMBL Grenoble characterized the structure of an important trypanosomal protein ...

It is designed to enable targeted muscle tissue delivery with the goal of reducing toxic DMPK RNA in the nucleus, releasing splicing proteins, allowing normal mRNA processing and translation of normal ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...

The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.

该研究揭示了肠道沙门氏菌如何通过非编码小RNA在转录后水平协调N-乙酰神经氨酸代谢过程中不同氨基糖操纵子转录产物的机制。 唾液酸是一类以九碳糖神经氨酸为基本结构的衍生物。生命体中常见的唾液酸为N-乙酰神经氨酸，富集于哺乳动物上皮细胞表面。