Existing research indicates that exosomal long non-coding RNAs (lncRNAs) play a crucial regulatory role in the initiation and progression of tumors, involving various interactions such as lncRNA-miRNA ...
As a result, m6A modifications may be a key factor in the pathogenesis of MAFLD, providing new insights into disease mechanisms and potential therapeutic targets. Moreover, lncRNA-GAS5 and its target ...
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近日,中国科学院上海有机化学研究所生物与化学交叉研究中心胡姣姣博士及刘聪研究员受邀在 Molecular Cell 杂志发表题为 “LncRNAs chaperoning dynamic protein condensates in cancer cells” 的文章,对同期同刊发表的关于 lncRNA 调控蛋白相分离的相关研究进行了深度解读与 ...
肝细胞癌(HCC)是肝脏最常见的原发性恶性肿瘤,占肝癌病例的75%~85%,是全球第六大常见的恶性肿瘤,也是癌症相关死亡的 ...
The prehybridized slides were then incubated with lncRNA-probe in hybridization solution at 37°C for 16 h. After hybridization, the slides were washed six times with prewarmed wash buffer and PBS ...
该研究首次发现,肠道微生物群通过抑制长链非编码RNA(lncRNA)Snhg9,发挥限制结直肠肿瘤发生发展的作用。 肠道微生物群是结直肠癌(CRC ...
该研究首次发现,肠道微生物群通过抑制长链非编码RNA(lncRNA)Snhg9,发挥限制结直肠肿瘤发生发展的作用。 肠道微生物群是结直肠癌(CRC)发生发展的关键环境因素。该研究发现,在结肠轻度炎症的情况下,肠道微生物群对小鼠结直肠肿瘤的发生具有保护作用。