2023年6月12日 · Research shows that stress can cause inflammation in the body, leading to a number of chronic health conditions. Find out what to do about it.

Here we discuss the role of inflammation in stress-induced diseases and suggest a common pathway for stress-related diseases that is based on chronic mild inflammation. This framework highlights the fundamental impact of inflammation mechanisms and provides a new perspective on the prevention and treatment of stress-related diseases.

Stress impairs the immune system in a dualistic fashion; the innate immune system upregulates pro-inflammatory genes, while the adaptive immune system down-regulates expression of Type I interferon- and antibody-related genes, weakening the antiviral response (Cole, 2014).

Herein we will review the immunology of acute and chronic stress exposure, integrate this discussion with the emerging literature linking heightened immune activation and inflammation to mood and anxiety disorders, and consider the translational implications of the immune system’s role in these psychiatric conditions.

2014年4月24日 · Inflammation is traditionally considered a defense response induced by infection or injury. However, inflammation can also be induced by tissue stress and malfunction in the absence of infection or overt tissue damage. Here we discuss the relationship between homeostasis, stress responses, and inflammation.

2019年7月1日 · The goal of this review is to first provide an overview of the current state of the human stress literature with regard to inflammatory responses to initial acute stress, and second, with regard to stimulation of systemic low-grade inflammation in chronic stress, and to finally move to discussing the transitional phase, in which acute stress ...

2005年3月1日 · Stressors can increase susceptibility to infectious agents, influence the severity of infectious disease, diminish the strength of immune responses to vaccines, reactivate latent herpesviruses...

This chapter reviews the basic physiological processes of inflammation, the relationships among aging, stress, and inflammation, and putative behavioral and physiological mechanisms linking stress and inflammaging, including the role of negative emotions, sleep, physical activity, diet, obesity, and social relationships.

2019年7月1日 · Chronic psychosocial stress is associated with systemic low-grade inflammation. A gap in our knowledge exists with regard to the time before an acute stressor becomes chronic. Studies on repeated acute stress might help fill this gap. Stress responses help us navigate our environment and respond appropriately to threats.

2014年4月24日 · Inflammation is traditionally considered a defense response induced by infection or injury. However, inflammation can also be induced by tissue stress and malfunction in the absence of infection or overt tissue damage. Here we discuss the relationship between homeostasis, stress responses, and infla …